Probiotics: A Helping Hand Toward a Fitter Life
Metabolic health encompasses different organs such as the liver, intestinal tract, the body’s fat stores, the muscles, heart and brain tissue. Overall, metabolic health is defined by the proper functioning of these organs, ensuring both quality of life and longevity. In most industrialized countries, populations show reduced gut microbial diversity compared to more traditional populations, and this decline in microbial diversity correlates with the rising prevalence of metabolic disorders. Scientific evidence indicates a strong link between the gut microbiota and metabolic health. And as far as gut microbiota is involved, probiotics can play a role.
Lallemand Health Solutions has gained innovative indications for its probiotic strain L. rhamnosus HA-114 from Health Canada, recognizing its beneficial impact to support people’s efforts when engaged in a weight management program, at a daily dose of 10B CFU.
Lallemand Health Solutions’ rising star L. rhamnosus HA-114 revealed to improve eating and mood-related behaviors in overweight adults who were undergoing diet-induced weight loss in a new breakthrough study.
Lallemand Health Solutions has gained new indications for its documented Expert’Biotic™ L. helveticus Lafti® L10 from Health Canada recognizing its antioxidant properties, with a specific focus for athletes’ health.
A clinical study on healthy adults with a high waist circumference demonstrated that B. lactis Lafti® B94 and Bacillus subtilis Rosell®-179 were able to increase plasma deconjugated bile acids, and a trend toward an increase in plasma HDL was observed for L. plantarum HA-119 after six weeks of intake. These results demonstrate the potential of those strains in the activation of the cycling of bile salts involved in cholesterol metabolism, and more generally, in the maintenance of a healthy bile salt metabolism, essential in metabolic health.
Learn more in our white paper on metabolic health!
In this document, we aim to shine a light on the connections that keep our human machinery running well and metabolically healthy. Along the way, discover how Lallemand Health Solutions’ probiotics lend a helping hand toward a fitter life.
Metabolic health is a topic of interest with many sub-categories of probiotics health applications. Some details are explained in our blog articles:
Probiotics have demonstrated to support metabolic health in different ways
Probiotics can help in the maintenance of a healthy metabolic profile, by increasing HDL cholesterol, commonly known as the “good cholesterol” and decreasing LDL cholesterol, the “bad cholesterol”, as well as triglycerides. L. helveticus Lafti® L10 have been shown to decrease LDL and increase HDL cholesterol (in comparison to baseline) in athletes [Michalickova, 2018]. Probiotics can also help modulate insulin levels and decrease insulin resistance, often seen in overweight populations. Probiotics, through their bile salt hydrolase activity, have also been shown to activate the cycling of bile salts involved in cholesterol metabolism and in the maintenance of a healthy bile salt metabolism, essential in metabolic health. Lallemand Health Solutions’ probiotic strains B. subtilis Rosell®-179 and B. lactis Lafti® B94 have been shown to deconjugate bile acids in healthy overweight adults [Culpepper, 2019].
Probiotics can also help support weight management efforts. By promoting a well-balanced brain-gut axis communication, probiotics can help improve eating behaviors, allowing to maintain a healthy weight, essential in supporting a healthy metabolism. In a recent, randomized, double-blind, placebo-controlled clinical trial [Choi, 2021 – Submitted], the effect of L. rhamnosus HA-114 was demonstrated to show positive results on eating and mood-related behaviors, as well as on metabolic parameters on overweight otherwise healthy adults on a diet.
Lastly, probiotics for other uses than food and dietary supplements have been demonstrated to support liver health in the context of liver diseases such as Non-Alcoholic Fatty Liver Disease (NAFLD) and Alcoholic Liver Disease (ALD).