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Probiotics For Mental Health

Psychobiotics: For a Balanced Microbiome-Gut-Brain Axis

Now considered in many countries as a mainstream probiotic application, mental health is influenced by the gut-brain connection. The communication between the gut and the brain is bidirectional and intensifies in times of stress. Psychological stress can impact the gastroenteric well-being, and vice versa.

Recently, the microbiome has been recognized as a third interlocutor in this relation and the microbiome-gut-brain axis concept has emerged. The microbiome-gut-brain axis is increasingly studied in regulating stress-related responses. Lallemand Health Solutions is a pioneer in the field of psychobiotics. Since 1929, we have been researching and developing probiotic solutions for mental health. New opportunities in stress management through the gut-brain axis are coming forth, such as the use of psychobiotics like Cerebiome® (L. helveticus Rosell®-52 and B. longum Rosell®-175).

Cerebiome® is a pioneering psychobiotic with game-changing science and a 15-year history of safe use. It is the most documented probiotic to support a healthy response to everyday occasional stress. Already in 2008, a study showed that Cerebiome® significantly reduced gut disturbances induced by psychological stress in healthy people.

In 2010, a pioneering clinical study was published showing that Cerebiome® significantly decreased the psychological stress and its symptoms such as anger-hostility in stressed, but healthy, volunteers in a gold standard clinical study [Messaoudi, 2010]. This study was a huge step for the gut-brain axis and is recognized as a reference in literature. Cerebiome® is part of the Expert’Biotic offer, which includes other innovative probiotic solutions for the gut-brain axis. Lacidofil® formula can protect against the negative effects of early-life stress and generational stress and B. bifidum Rosell®-71, can help students cope with academic stress.  

Latest news

Cerebiome®

  • Apsen Farmaceutica, Lallemand Health Solutions’ commercial partner in Brazil, published a new positive results study, confirming that Cerebiome® exerts a positive influence on the gut microbiota of individuals with mild anxiety.
  • A new post-hoc analysis confirmed in humans that Cerebiome® can significantly increase brain-derived neurotrophic factor serum levels as observed several years ago in preclinical models. These new results bring more understanding about the potential modes of action of Cerebiome® on the gut-brain axis.

Lacidofil®

  • New results showed that Lacidofil® protects from early-life stress which predisposes individuals to increase feelings of anxiety in adulthood. In a new in vivo study, early intake of Lacidofil® prevented early-life stress consequences in rodents. This is the seventh study documenting various positive effects of this specific probiotic formula in early-life stress.

More news

As a co-founding partner, Lallemand Health Solutions proudly presents the fourth edition of the Mind, Mood & Microbes International conference on Microbiome-Gut-Brain axis, which will take place in Amsterdam, the Netherlands, on 10-11 May 2023. The event will gather an unmatched line-up of leading scientists, healthcare professionals, and industry partners from complementary fields to share new developments and findings about micro-organisms impact on the brain-gut axis and mental wellness. Read more
Apsen Farmaceutica, Lallemand Health Solutions’ commercial partner in Brazil, is publishing new positive results on the influence of Cerebiome® on the gut microbiota of individuals with mild anxiety. Read more
Frost & Sullivan has identified Cerebiome® by Lallemand Health Solutions as the world’s most proven psychobiotic, a major differentiator compared to competitors in the probiotics for mental health space. Lallemand Health Solutions has earned Frost & Sullivan’s 2021 Product Leadership Award in the European psychobiotics industry, recognizing Cerebiome®’s ability to deliver the best quality, reliability, overall performance, and strong market positioning. Read more
Infantile stress predisposes individuals to higher anxiety in adulthood. In a new in vivo study, early intake of Lacidofil® (Lallemand Health Solutions proprietary combination of L. rhamnosus Rosell®11 and L. helveticus Rosell®-52) prevented early-life stress consequences in rodents. This is the seventh study documenting various positive effects of this specific probiotic formula in early-life stress. Read more

On World Mental Health Day, we jump on the bandwagon to raise awareness about mental well-being around the world and to mobilize efforts in support of mental health care.

The World Health Organization defines mental health as “a state of mental well-being that enables people to cope with the stresses of life, realize their abilities, learn well and work well, and contribute to their community”. With globally one third of consumers that are not satisfied with their mental well-being[1] it is indeed quite concerning and worth talking about. Read more

According to the World Health Organization (WHO), stress is a common health issue across the globe. In the last two years, this health concern has been exacerbated as people worldwide are struggling to cope with the disruptions that the COVID-19 pandemic has caused, and half of people state they experience stress most of the time or all the time. Read more
Several scientific studies have been conducted using an approach to modify the nutrition of subjects to evaluate the association between diet, the gut microbiome and mental health. These studies have linked psychiatric disorders such as depression to changes in the microbiome of the gastrointestinal tract, making probiotics a supportive solution for targeting mental well-being. Probiotics have shown the ability to improve behavior, mood, anxiety, stress, and improve depression-like symptoms (Liu 2019, Del Toro-Barbosa 2020, Tremblay 2021). Read more
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