New Review Highlights the Oral Health Benefits of Oralis SB

Mirabel, September 16, 2025 – A newly published scientific review[1] consolidates the clinical evidence supporting Oralis SB, Lallemand Health Solutions’ most studied probiotic formula for oral health. Backed by 13 clinical studies in adults and children, Oralis SB demonstrates significant benefits in maintaining oral health for healthy teeth and gums.
 
The review summarizes clinical trials using the Darolac® probiotic formulation (the commercial name of Oralis SB in India)— composed of L. helveticus Rosell®-52, L. rhamnosus Rosell®-11, B. longum Rosell®-175, and S. boulardii CNCM I-1079— used in powder form to mix with water as a mouthwash, to support oral microbiome balance.
 
In these studies, Oralis SB is explored as an alternative solution to conventional mouthwashes by restoring homeostasis in the oral cavity to promote oral health. Oralis SB was compared to placebo and conventional mouthwashes such as chlorhexidine. This review highlights the effectiveness of Oralis SB to promote oral health through the control of S. mutans growth, the maintenance of healthy gums and a healthy salivary pH. Interestingly, when compared to conventional mouthwashes, Oralis SB was shown to be equally or more effective than the studied mouthwashes, reinforcing its role as a natural
 
and effective alternative in oral care. The review also explores the general importance of a balanced oral microbiome through markers of dysbiosis and highlights the growing relevance of probiotics in the periodontal field.
 
Oralis SB: Clinically Documented Benefits

Oralis SB has been studied in over 700 participants through 13 clinical trials on various oral health applications:

 
Camille Binachon, Marketing Group Manager and responsible for the Oral Health portfolio, commented: “Oral health issues often stem from imbalances in the oral microbiome. Probiotics provide a science-backed, natural approach to support healthy teeth, gums, and mouth. With 13 clinical trials along with 4 mechanistic studies on modes of action, Oralis SB meets consumer expectations for both efficacy and naturalness.”
 
Thanks to its robust clinical backing, Oralis SB has been acknowledged in Canada to:

Oralis SB is available in orodispersible powder or ingestible mouthwash. Furthermore, Lallemand Health Solutions offers a comprehensive range of probiotics for additional benefits on oral health.

About Lallemand Health Solutions – Leading Probiotics Forward
With 90 years of expertise, Lallemand Health Solutions is a global leader in probiotics, specializing in the development, production, and marketing of bacteria- and yeast-based supplements for human health, nutricosmetics, and food applications. Our facilities meet the highest quality standards, including GMP certification, and our research is driven by the Rosell Institute for Microbiome and Probiotics. We offer clinically documented probiotic strains for gut health, immune support, mental well-being, women’s health, skin and oral health, sports, metabolic health, healthy aging, and infant health.

Media Contact
Marilou Luneau Communications Manager, Lallemand Health Solutions
[email protected]

[1]https://www.researchgate.net/publication/388990547_Effect_of_the_Darolac_Oralis_SB_Probiotic_Formulation_on_Oral_Health_A_Narrative_Review